“She’s hands-down the best litigator I’ve ever met. She has phenomenal strategic vision and great jury presence.” - Client to Chambers 

Enu is a nationally recognized trial lawyer with particular expertise in health care and pharmaceuticals, financial services and the False Claims Act. She has been leading investigations and trying cases for over 25 years and is a member of the Firm’s Executive Committee. 

Chambers USA (2022-2023) has ranked Enu in Band 1 for Commercial Litigation and False Claims Act Litigation, noting that she “wins impressive praise from clients,” who describe her as “a go-to person, a powerhouse” with “a tremendous record in her cases,” “really strategic” and “business savvy,” and a “rockstar of the first order.” Chambers further noted that “she’s at the top of her game with a number of great clients and really high-profile cases.” “She is a very practical, engaging, quick-on-her-feet lawyer.” Finally, another client noted, “she’s hands-down the best litigator I’ve ever met. She has phenomenal strategic vision and great jury presence.”

Enu has also been widely recognized by other legal publications. In 2020 The National Law Journal recognized Enu in its special report on “Masters of the Courtroom: 2020 Winning Litigators,” highlighting 26 lawyers who “tackled some of the most widely watched cases of the year.” She has been named a “Health Care MVP” multiple times by Law360 (2017, 2019, 2021). In 2019, Enu was named a “Health Care Law” Trailblazer by The National Law Journal. The Legal 500 notes that clients report Enu Mainigi is “who you want thinking and talking on your behalf before a judge or a jury.”  She is “fantastic and very strong in oral advocacy, among other things.” Benchmark Litigation has on multiple occasions named Enu a “Local Litigation Star” and a “National Litigation Star” in the area of white-collar crime and investigations, and among the “Top 250 Women in Litigation.” She has been recognized as a BTI Client Services All-Star, has been named a Life Science Star by LMG Life Sciences, and in 2020 was honored as one of eight finalists for Litigator of the Year by The American Lawyer.  

Clients turn to Enu for their most important matters in various areas. Recent examples include:  

Trials: In the last year alone, Enu has first chaired three trials and two arbitrations, including a landmark 3-month-long opioid trial in West Virginia federal court that resulted in a complete defense verdict for Cardinal Health and a certified consumer class action jury trial for CVS Health in the Northern District of California that resulted in a complete defense verdict. In 2019, Enu and her team scored a major victory on behalf of CVS in a jury trial proceeding against the Texas Attorney General that could have resulted in CVS’s exclusion from Texas Medicaid, winning instead a directed verdict after a several-week trial where the state alleged Medicaid fraud against CVS under the Texas equivalent of the False Claims Act. 

Government Investigations: A consistently significant part of Enu’s practice is the representation of a broad spectrum of corporate institutions and individuals in civil fraud and criminal investigations. She has led the defense of over 80 False Claims Act investigations, and Chambers notes Enu has a “tremendous record” in False Claims Act cases, earning her a Band 1 ranking in Chambers inaugural False Claims Act Litigation rankings.  

Health Care: Enu is actively sought out by large and small players in the healthcare industry to lead their high stakes, bet-the-company litigation. Over the last 23 years, in these matters, Enu has garnered impressive victories. These have often been the result of pragmatically litigating novel or difficult issues. Chambers noted that clients describe Enu as “extremely knowledgeable on the law and regulations, but also practical in getting to a solution.” As a result, Enu has developed an impressive stable of top health care companies as clients, including as lead counsel for health care companies such as CVS Health, Cardinal Health, and Omnicare (as well as smaller health care companies) on their most high stakes cases. Enu is currently lead national counsel for Cardinal Health on all opioid-related matters – civil litigation and state AG – which are the highest stakes litigation ever seen by the industry.  

In addition to serving as lead counsel on significant matters for these companies, Enu often plays an advisory and strategic role to their senior legal and business leadership.  

Financial Services: From 2013 – 2016, Enu led the representation of Bank of America against the SDNY involving the novel use of FIRREA related to mortgages associated with the financial crisis. The Second Circuit ultimately awarded the Bank a complete win. Enu is currently set to lead the trial team for a bank in one of the last of the financial crisis litigations in the fall of 2022. Enu also represents banks in significant matters involving government regulators including the CFPB and the OCC.  

In addition to serving on the Executive Committee, Enu serves as Chair of the firm’s False Claims Act and Qui Tam practice and Co-chair of its Health Care practice.  




“False Claims Act (Nationwide),” Chambers USA, 2022-2023

"Litigation: General Commercial (D.C.)," Chambers USA, 2020-2023

“Healthcare (D.C.),” Chambers USA, 2015-2023

"Litigation: Trial Lawyers," Chambers USA (Nationwide), 2023

Finalist for "Litigator of the Year," by The American Lawyer, 2020, 2022-2023

"Winning Litigator," The National Law Journal, 2020, 2023

"Top 100 Trial Lawyers in America," Benchmark Litigation, 2023

“National Litigation Star,” Benchmark Litigation, 2017-2024

“Local Litigation Star,” Benchmark Litigation, 2015-2024

"Trials MVP," Law360, 2023

Recognized with "Impact Case Award” for Cardinal Health win, Benchmark Litigation, 2023

"Class Action/Mass Tort Litigation Trailblazer," The National Law Journal, 2023

Recommended for Healthcare Law, Who’s Who Legal: Healthcare 2020

"Health Care Law Trailblazer," The National Law Journal, 2019

“500 Leading Litigators in America,” Lawdragon, 2023-2024

“Top 250 Women in Litigation,” Benchmark Litigation, 2015-2022

“Life Science Star,” LMG Life Sciences, 2018-2023

BTI Client Service All-Stars, 2019

“Health MVP,” Law360, 2017, 2019, 2021

“Outstanding Women Lawyers,” The National Law Journal, 2015

“Female Powerbrokers Q&A: Williams & Connolly's Enu Mainigi,” Law360, 2014


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